Advisor, Upstream Process Development          

Eli Lilly and Company             

January 2023Present

o   Leading the design and execution of upstream process development studies in baculovirus/Sf9 systems for AAV gene therapy drug substances in benchtop scale bioreactors

o   Developing platform process to screen and optimize process conditions for new pipeline products

o   Assisting research material generation needs for new pipeline products

o   Providing technical expertise in cell culture scale-up, bioreactor process parameters, process control strategy, and media additive strategies

o   Building process understanding to support technology transfer to internal or external groups for manufacturing at pilot, engineering, clinical, or commercial scales

o   Developing new production lab to scale up AAV production for rare disease treatment


Graduate Research Assistant          

3D-Tissue Manufacturing Research Group at NC State               

December 2019 – December 2022


        Evaluated differentiation of stem cells (hASCs) in 3D scaffolds and hydrogels using nondestructive techniques

        Worked with various mammalian cell lines (hASCs, Chondrocytes, 3T3, MG63, C2C12) and E. Coli

        Developed novel nondestructive quality evaluation system for engineered tissue constructs

Planned and executed designed experiments to systematically characterize CQA of impedance spectroscopy.

Analyzed the Dielectric Spectroscopy signals by developing a custom-coded python script for quality monitoring

Evaluated the patterns associated with engineered tissues using machine learning and deep learning algorithms

Developed a GUI using python to track the historical quality attributes automatically for long term studies

Developed scalable multi-modal perfusion based novel tissue bioreactor system for quality monitoring

Co-authored 3 poster presentations,  5 oral presentations, 1 conference proceeding, and 4 working manuscripts.


Laboratory Manager                             

3D-Tissue Manufacturing Research Group at NC State                           

April 2021 – December 2022


o   Optimized laboratory inventory, ordering, and stocking workflows for BSL-2 cell culture lab.

o   Liasoned with life science sales representatives to plan capital purchases and lead product demonstrations.

o   Represented 3D-Tissue Manufacturing Research Group at cross-functional and institute meetings.


Graduate Teaching Assistant at NC State

August 2018 – December 2019

o   Assisted students on their class lectures, assignments, and projects through office hours and one-on-one communication

Associate Member Principal Investigator        

Comparative Medicine Institute at NC State               

January 2021 – July 2021


·      Secured and managed $8,000 in internal research capital through NIH-style grant application

·      Built cross-functional teams of material scientists, engineers, cell biologists to achieve project goals

·      Managed and mentored undergrad students in collaborative team science environment

Society for Manufacturing Engineers (SME) Student Chapter, ISE, NCSU

President

April 2021April 2022

Vice President                                       

 April 2020 – April 2021


Comparative Medicine Institute at NC State                                                  

2019 – 2022

FTE Associate Member


Institute of Industrial and Systems Engineers

March 20212022

Student Member